University of Minnesota Children’s Hospital, Fairview Position(s)
Transplant Surgeon

Other Related Positions Currently Held
Professor, General & Transplant Surgery

Chief, Division of Transplantation, Department of Surgery, University of Minnesota

Director, Diabetes Institute for Immunology and Transplantation

Director, Pancreas Transplant Program

Board Certifications
Surgery

Sees Patients At
- University of Minnesota Children’s Hospital, Fairview
- Transplant Center (Minneapolis)

Clinical Interests
Auto Islet Transplantation
Chronic Pancreatitis
General Surgery
Islet Transplant
Kidney Transplant
Pancreas Transplant
Transplant Surgery

Education
Medical School
University of Minnesota

Site of Residency
West Virginia University Hospital, University of Minnesota

Site of Fellowship
University of Minnesota (Transplantation)

Awards and Honors
Best Doctors in America®, 2007-2008

Research Interest(s)
Pancreas and Islet Transplantation
Immunobiology of Transplant Rejection

Selected Recent Publications
Humar, A., Kandaswamy, R., Granger, D. K., Gruessner, R. W. G., Gruessner, A., and Sutherland, D. E. R. Decreased surgical risks of pancres transplantation in the modern era. Ann. Surg. 231:269-275, 2000.

Gruessner, A. and Sutherland, D. E. R. Analyses of pancreas transplant outcomes for United States cases reported to the United Network for Organ Sharing (UNOS) and non-US cases reported to the International Pancreas Transplant Registry (IPTR). In J. M. Cecka and P. I. Terasaki (Eds.), Clinical Transplants 1999. Los Angeles: UCLA Immunogenetics Center, 2000. Pp. 51-69.

Humar, A., Parr, E., Drangstveit, M. B., Kandaswamy, R., Gruessner, A., and Sutherland, D. E. R. Steroid withdrawal in pancreas transplant recipients. Clin. Transplant. 14:75-78, 2000.

Humar, A., Durand, B., Gillingham, K. J., Payne, W. D., Sutherland, D. E. R., and Matas, A. J. Living unrelated donors in kidney transplants. Transplantation 69:1942-1945, 2000.

Sutherland, D. E. R., Gruessner, R. W. G., Mauer, S. M., and Gruessner, A. Pancreas transplantation. In D. LeRoith, S. I. Taylor, and J. M. Olefsky (Eds.), Diabetes Mellitus: A Fundamental and Clinical Text. Philadelphia: Lippincott Williams & Wilkins, 2000. Pp. 518-526.

Merion, R. M., Henry, M. L., Melzer, J. S., Sollinger, H., Sutherland, D. E. R., and Taylor, R. J. Randomized, prospective trial of mycophenolate mofetil versus azathioprine for prevention of acute renal allograft rejection after simultaneous kidney-pancreas transplantation. Transplantation 70:105-111, 2000.

Humar, A., Gillingham, K. J., Payne, W. D., Sutherland, D. E. R., and Matas, A. J. Increased incidence of cardiac complications in kidney transplant recipients with cytomegalovirus disease. Transplantation 70:310-313, 2000.

Matsumoto, S., Kandaswamy, R., Sutherland, D. E. R., Hassoun, A., Hiraoka.K., Sageshima, J., Shibata, S., Tanioka, Y., and Kuroda, Y. Clinical application of the two-layer (University of Wisconsin Solution/Perfluorochemical plus O2) method of pancreas preservation before transplantation. Transplantation 70:771-774, 2000.

Sells, R. A. and Sutherland, D. E. R. Is there a role for sole transplantation of the pancreas (without the kidney) in type 1 diabetes? In G. Gill, J. Pickup, and G. Williams (Eds.), Difficult Diabetes. Oxford: Blackwell Science, Ltd., 2000. Pp. 224-234.

Nyberg, S. L. and Sutherland, D. E. R. Fecalith impaction of the terminal ileum in a diabetic transplant recipient. Am J Gastroenterol 95:3286-3287, 2000.

Humar, A., Sutherland, D. E., Ramcharan, T., Gruessner, R. W., Gruessner, A. C., and Kandaswamy, R. Optimal timing for a pancreas transplant after a successful kidney transplant [In Process Citation]. Transplantation 70:1247-1250, 2000.

Papalois, V. E., Moss, A., Gillingham, K. J., Sutherland, D. E., Matas, A. J., and Humar, A. Pre-emptive transplants for patients with renal failure: an argument against waiting until dialysis. Transplantation 70:625-631, 2000.

Humar, A., Payne, W. D., Sutherland, D. E., and Matas, A. J. Clinical determinants of multiple acute rejection episodes in kidney transplant recipients. Transplantation 69:2357-2360, 2000.

Robertson, R. P., Davis, C., Larsen, J., Stratta, R., and Sutherland, D. E. Pancreas and islet transplantation for patients with diabetes. Diabetes Care 23:112-116, 2000.

Humar, A., Kandaswamy, R., Drangstveit, M. B., Parr, E., Gruessner, A. G., and Sutherland, D. E. Surgical risks and outcome of pancreas retransplants. Surgery 127:634-640, 2000.

Kronson, J. W., Gillingham, K. J., Sutherland, D. E., and Matas, A. J. Renal transplantation for type II diabetic patients compared with type I diabetic patients and patients over 50 years old: a single-center experience. Clin Transplant 14:226-234, 2000.

Humar, A., Kandaswamy, R., Drangstveit, M. B., Parr, E., Gruessner, A. G., and Sutherland, D. E. Prolonged preservation increases surgical complications after pancreas transplants. Surgery 127:545-551, 2000.

Matas, A. J., Gillingham, K., Payne, W. D., Humar, A., Dunn, D. L., Sutherland, D. E., and Najarian, J. S. Should I accept this kidney? Clin Transplant 14:90-95, 2000.

Matas, A. J., Gillingham, K. J., Humar, A., Dunn, D. L., Sutherland, D. E., and Najarian, J. S. Immunologic and nonimmunologic factors: different risks for cadaver and living donor transplantation [see comments]. Transplantation 69:54-58, 2000.

Robertson RP, Lanz KJ, Sutherland DE, Kendall DM. Prevention of diabetes for up to 13 years by autoislet transplantation after pancreatectomy for chronic pancreatitis. Diabetes 2001; 50:47-50.

Sutherland DE, Gruessner RWG, Dunn DL, Matas AJ, Humar A, Kandaswamy R, Mauer SM, Kennedy WR, Goetz FC, Robertson RP, Gruessner AC, Najarian JS. Lessons learned from more than 1,000 pancreas transplants at a single institution. Ann Surg 2001; 233:463-501.

Gruessner AC, Sutherland DER. Pancreas transplant outcomes for United States (US) cases reported to the United Network for Organ Sharing (UNOS) and non-US cases reported to the International Pancreas Transplant Registry (IPTR) as of October, 2000. In Cecka JM, Terasaki PI (eds). Clinical Transplantation 2000. Los Angeles: UCLA Immunogenetics Center; 2001:45-72.

Sutherland DER, Gruessner RWG, Gruessner A. Pancreas transplantation for treatment of diabetes mellitus. World J Surg 2001; 25:487-496.
Wu T, Hering BJ, Kirchhof N, Sutherland DE, Yagita H, Guo Z. The effect pf PX40/)X40L and CD27/CD70 pathways on allogeneic islet graft rejection. Transplant Proc 2001; 33:217-218.

Shibata S, Matsumoto S, Sageshima J, Hiraoka.K., Sutherland DE, Kirchhof N, Guo Z, Koyama K, Gilmore T, Dunning M, Ansite JD, Shearer S, Clemmings SM, Hedlund BE, Sehgal SN, Hering BJ. Temporary treatment with Sirolimus and low-trough Cyclosporine prevents acute islet allograft rejection, and combination with starch-conjugated Deferoxamine promotes islet engraftment in the preclinical pig model. Transplant Proc 2001; 33:509-509.

Gruessner RWG, Sutherland DE, Drangstveit MB, Bland BJ, Gruessner AC. Pancreas transplants from living donors: Short-and long-term outcome. Transplant Proc 2001; 33:819-820.
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Hiraoka.K., Trexler A, Fujioka B, Guo Z, Zhang HJ, Overland A, Oberbroeckling J, Sageshima J, Shibata S, Sutherland DER, Hering BJ. Optimal temperature in pancreas preservation by the two-layer cold storage method before islet isolation. Transplant Proc 2001; 33:891-892.

Hiraoka.K., Trexler A, Eckman E, Stage A, Nevile S, Sageshima J, Shibata S, Sutherland DER, Hering BJ. Successful pancreas preservation before islet isolation by the simplified two-layer cold storage method. Transplant Proc 2001; 33:952-953.

Kandaswamy R, Humar A, Payne WD, Dunn DL, Sutherland DER, Matas AJ. Risk factors for kidney transplant acute rejection: A multivariate analysis. Transplant Proc 2001; 33:1112.

Kandaswamy R, Sutherland DER, Humar A, Payne WD, Gruessner RWG, Matas AJ. Transplantation without a final crossmatch - It can be done. Transplant Proc 2001; 33:1234-1234.

Kandaswamy R, Gillingham K, Humar A, Payne WD, Dunn DL, Sutherland DER, Najarian JS, Matas AJ. Impact of HLA-ABDR match on chronic rejection in kidney transplants. Transplant Proc 2001; 33:1292-1292.

Gruessner A, Sutherland DER. Report for the International Pancreas Transplant Registry - 2000. Transplant Proc 2001; 33:1643-1646.

Sutherland DER, Gruessner RWG, Humar A, Kandaswamy R, Najarian JS, Dunn DL, Gruessner A. Pretransplant immunosuppression for pancreas transplants alone in nonuremic diabetic recipients. Transplant Proc 2001; 33:1656-1658.

Gruessner RWG, Sutherland DER, Parr E, Humar A, Gruessner AC. A prospective, randomized, open-label study of steroid withdrawal in pancreas transplantation - A preliminary report with 6-month follow-up. Transplant Proc 2001; 33:1663-1663.

Gruessner AC, Sutherland DER, Gruessner RWG. Matching in pancreas transplantation - A registry analysis. Transplant Proc 2001; 33:1665-1666.

Gruessner AC, Sutherland DER, Gruessner RWG. Enteric versus bladder drainage for solitary pancreas transplants - A Registry report. Transplant Proc 2001; 33:1678-1680

Sageshima J, Kirchhof N, Shibata S, Hiraoka.K., Sutherland DER, Hering BJ. Small bowel subserosal space as a site for islet transplantation and local drug delivery. Transplant Proc 2001; 33:1710-1710.

Brayman KL, Zamire GA, Sutherland DER. Pancreas transplantation. In Cameron JL (ed). Current Surgical Therapy. St. Louis: Mosby; 2001:578-586.

Hering BJ, Ricordi C, Sutherland DER, Bluestone JA. Pancreatic islet cell transplantation. In Norman DJ, Turka LA (eds). Primer on Transplantation. Mt. Laurel, NJ: American Society of Transplantation; 2001:512-518.

Humar A, Key N, Ramcharan T, Payne WD, Sutherland DER, Matas AJ. Kidney retransplants after initial graft loss to vascular thrombosis. Clin Transplant 2001; 15:6-10.

Guo Z, Kirchhof N, Mital D, Williams JW, Azuma M, Sutherland DER, Hering BJ. Immunotherapy with nondepleting anti-CD4 monoclonal antibodies but not CD28 antagonists protects islet graft in spontaneously diabetic nod mice from autoimmune destruction. Transplantation 2001; 71:1656-1665

Wrenshall LE, Ansite JD, Eckman PM, Heilman MJ, Stevens RB, Sutherland DER. Modulation of immune responses after portal venous injection of antigen. Transplantation 2001; 71:841-850.

Arrazola L, Sutherland DER, Sozen H, Hunter DW, Payne WD, Najarian JS, Matas AJ. May-Thurner syndrome in renal transplantation. Transplantation 2001; 71:698-702.