University of Minnesota Amplatz Children’s Hospital Position(s)
Director, Pediatric Critical Care and Pediatric Sedation Services
Pediatric Critical Care Trauma Liaison

Other Related Positions Currently Held
Professor, Division of Pulmonary and Critical Care, Department of Pediatrics, University of Minnesota

Specialties
Critical Care
Cardiology
Imaging and Sedation
Trauma Services

Board Certifications
Pediatrics
Pediatric Critical Care
National Board of Examiners

Sees Patients At
University of Minnesota Amplatz Children’s Hospital
Pediatric Specialty Clinic (Minneapolis)
Sedation & Imaging Center

Clinical Interests
Acute lung injury
Heart failure
Pulmonary hypertension
Postoperative cardiac care
Sepsis
Trauma

Education
Medical School
Vanderbilt University School of Medicine, Nashville, Tenn.

Site of Internship & Residency
Vanderbilt University School of Medicine, Nashville, Tenn.

Site of Fellowship
Children's Hospital of Alabama, University of Alabama at Birmingham           

Awards and Honors
Mpls.St.Paul Magazine Top Doctors 2010
Best Doctors in America®, 2009-2010
Mpls.St.Paul Magazine Top Doctors 2009

Selected Recent Publications
Malhotra V, Kooy NW, Denenberg AG, Dunsmore KE, Wong HR. Ablation of the heat shock factor-1 increases susceptibility to hypoxia-mediated cellular injury. Experimental Lung Research 2002;28:609-622.

Uc A, Murray JA, Kooy N, Conklin JL. Effect of peroxynitrite on motor function of the opossum esophagus. Digestive Diseases and Sciences 2001;46:30-37.

Lamb FS, Kooy NW, Lewis SJ. Hemodynamic effects of 4,4,'-diisothiocyanotostilbene-2, 2'-disulfonic acid (DIDS) in the rat. European Journal of Pharmacology 2000;401:403-412.

Ischiropoulos H, Gow A, Thom SR, Kooy NW, Royall JA, Crow JP. Detection of reactive nitrogen species using 2, 7-dichlordihydrofluorescein and dihydrorhodamine 123. Methods in Enzymology 1999;301:367-373.

Benkusky NA, Lewis SJ, Kooy NW. Peroxynitrite-mediated attenuation of the in vivo hemodynamic responses to a- and B- adrenoceptor agonists. European Journal of Pharmacology, 1999;364:151-158.

Benkusky NA, Lewis SJ, Kooy NW. Attenuation of vascular relaxation following the devleopment of tachyphylasis to peroxynitrite in vivo. American Journal of Physiology, 1998;275:H501-H508.

Graves JW, Lewis SJ, Kooy NW. Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols. American Journal of Physiology. 1998;274:H1001-H1008.

Gilman AL, Kooy NW, Atkins DL, Ballas Z, Rumelhart S, Holida M, Lee N, Goldman F. Complete heart block in association with graft-versus-host disease. Bone Marrow Transplantation, 1998;21:85-88.

Kooy NW, Royall JA, Ischiropoulos H. Oxidation of 2',7'-dichlorofluoroscin by peroxynitrite. Free Radical Research Communications, 1997;27:245-254.

Kooy KW, Lewis SJ, Royall JA, Ye YZ, Kelly DR, Beckman JS. Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite. Critical Care Medicine, 1997;25:812-819.

Kooy N.W, Lewis SJ. The peroxynitrite produce 3-nitro-L-tyrosine attenuates the hemodynamic responses to angiotensin II in vivo. European Journal of Pharmacology, 1996;315:165-170.

Kooy NW, Lewis SJ. Nitrotyrosine attenuates the hemodynamic effects of adrenoceptor agonists in vivo: relevance to the pathophysiology of peroxynitrite. European Journal of Pharmacology 1996;310:155-161.

Kooy NW, Lewis SJ. Elevation in arterial blood pressure following the development of tachyphylasis to peroxynitrite. European Journal of Pharmacology. 1996;307:R5-R7.