University of Minnesota Children’s Hospital, Fairview Position:
Pediatric Cardiologist
Other Related Positions Currently Held:
Associate Professor, Pediatrics, Department of Pediatric Cardiology, University of Minnesota
Board Certifications:
Pediatrics
Pediatric Cardiology
Neonatal-Perinatal Medicine
Did you Know?
> After his residency, Dr. Kochilas served one year in Greek Air Force medicine, focusing on caring for and transporting critically ill patients
> From 2000 to 2008, Dr. Kochilas lead an NIH-funded research program focused on the mechanisms of normal and abnormal cardiac development
Sees Patients At:
-University of Minnesota Children’s Hospital, Fairview
-Pediatric Specialty Clinic (St. Paul)
Clinical Interests:
-General Pediatric Cardiology
-Echocardiography
-Genetics of Congenital Heart Diseases
Education:
Medical Schools –
National and Kapodistrian University of Athens, Greece
University of Athens, Department of Internal Medicine
Sites of Residency –
University Children’s Hospital, Heldelberg, Germany (Pediatrics)
University of Texas Health Science Center at Houston (Pediatrics)
Sites of Fellowship –
Thomas Jefferson University, Philadelphia (Neonatal-Perinatal Medicine)
Children’s Hospital of Philadelphia (Pediatric Cardiology)
Awards & Honors:
-Reviewer: Pediatrics
Archives of Disease in Childhood
-Member of the Society for Pediatric Research (2003- )
-American Academy of Pediatrics (Sections of Pediatric Cardiology and Neonatal Perinatal Medicine) (1996- )
-American Heart Association (Basic CV Science Council and Cardiovascular Disease in the Young) (1999- )
Selected Recent Publications:
Articles & Abstracts:
B. Funke, J. Epstein, L. Kochilas, M. Lu, R. Pandita, J. Liao, R. Bauerndistel, T. Schüller, C. Brown, H. Schorle, J. Adams and B. Morrow. “Mice overexpressing genes from the 22q11 region deleted in velo-cardio-facial syndrome/DiGeorge syndrome have middle and inner ear defects.” Human Molecular Genetics 2001, 10(22) 2549-2556.
L.Kochilas, R. Tanel. “Syncope in the infant and the newborn.” Progress in Pediatric Cardiology 2001; 13: 71-82.
A. Gitler, C. Brown, L. Kochilas, J. Li, JA Epstein. “ Neural Crest migration and mouse models of congenital heart disease.” The Cold Spring Harbor Symposia on Quantitative Biology 2002; 67:57-62.
L. Kochilas, S. Merscher-Gomez, M. Lu, V. Potluri, J. Liao, R. Kucherlapati, B. Morrow, J. Epstein. “The role of neural crest during cardiac development in a mouse model of DiGeorge syndrome.” Devel Biology 2002; 251, 157-166.
L. Kochilas, V. Potluri, A. Gitler, K. Balasubramanian, A. Chin. "Cloning and characterization of zebrafish tbx1." Mech Develop (Gene Expr Patterns) 2003, 3(5), 645-651.
J. Liao, L. Kochilas, S. Nowotschin, JS. Arnold, VS. Aggarwal, J.A. Epstein, M.C. Brown, J. Adams, B.E. Morrow. “Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage.” Human Molecular Genetics 2004; 13(15),1-9.
KG. Ackerman, BJ. Herron, SO. Vargas, H. Huang, L. Kochilas, C. Rao, B. Pober, RP. Babiuk, JA. Epstein, JJ. Greer, DR. Beier. “Mutations in Fog2 Cause Diaphragmatic Defects and Primary Pulmonary Hypoplasia in Mice and Man.” PLOS Genetics 2005, 1(1), e10 (001-007).
S. Ford, A. Rao, L. Kochilas. “Giant coronary artery aneurysm formation following meningococcal septicaemia.” Pediatr Cardiol 2007; 28(4): 300-302.
L. Kochilas, D. Abuelo, U. Tantravahi. “Congenital Polyvalvular Disease (CPVD) in a Patient with Inverted Duplication 2p21-23.” Pediatr Cardiol 2008; 29(1): 172-175.
L. Kochilas, F. Gundogan, M. Atalay, J.M. Bliss, M. Vatta, L. Smith Pena, D. Abuelo. “A Novel Mutation of the Fibrillin-1 (FBN1) Gene in a Patient with Neonatal Marfan Syndrome.” J Perinatol 2008; 28(4): 303-305.
J. Kreiling, Z. Balantac, J. Toure, S. Zchut, L. Kochilas, R. Creton. “Calcium Manipulation in Zebrafish Embryos Affects Left-Right Asymmetry of the Heart and Brain.” Mech Develop 2008; 125: 396-410.
S. Haley, T. Zhao, L. Jun, J. Klysik, J. Padbury, L. Kochilas. “Forced Expression of the Cell Cycle Inhibitor p57KIP2 in Cardiomyocytes Attenuates Ischemia-Reperfusion Injury in the Mouse Heart.” BMC Physiol 2008, 8:4doi:10.1186/1472-6793-8-4.
J. Kern, R. Modi, M. Atalay, L. Kochilas. “High Levels of Cardiac Troponin I Mimicking Acute Coronary Syndromes in Children with Myocarditis.“ J Pediatr (2008, in print).
Books and Book Chapters:
L. Kochilas. “Patent Ductus Arteriosus.” The 5 Minute Pediatric Consult. W. Schwartz, William & Wilkins (2nd Edition), Philadelphia, 2000; 600-601.
L. Kochilas, A. Chin. “Congenital Heart Disease.” Textbook of Molecular Medicine, M. Runge and W. Patterson, Humana (2nd Edition), Totowa, NJ, 2006, 69-97.




